RESUMO
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RESUMO
The enzyme-linked immunosorbent assay (ELISA) was used to detect and quantify antibodies to whole worm extract antigens of Dictyocaulus filaria. The results provided evidence that the test was highly sensitive and could be used as a tool for epidemiological studies. No cross reactions were observed with sera from lambs infected with the hookworm Gaigeria pachyscelis.
Assuntos
Infecções por Dictyocaulus/diagnóstico , Doenças dos Ovinos/diagnóstico , Ancylostomatoidea/imunologia , Animais , Anticorpos/análise , Antígenos de Helmintos/imunologia , Dictyocaulus/imunologia , Ensaio de Imunoadsorção Enzimática , Ovinos , Especificidade da EspécieAssuntos
Schistosoma/imunologia , Esquistossomose/imunologia , Animais , Reações Cruzadas , Feminino , Imunidade Ativa , Masculino , CamundongosRESUMO
The tissue reactions in mice, experimentally infected with normal and irradiated cercariae of S. incognitum were studied. The lesions observed in the skin, liver, lungs and the intestine of mice infected with normal cercariae are briefly described, and compared with those observed with cercariae irradiated at 3000 r of gamma rays. In general, the reactions in mice exposed to normal cercariae were more intense than in those infected with irradiated cercariae. The severity of the reactions appeared largely due to the deposition of eggs in the tissues of the mice infected with normal cercariae. The experimental evidence suggested that most of the flukes from the irradiated cercariae are destroyed in the liver by tissue reaction.
Assuntos
Esquistossomose/patologia , Animais , Radioisótopos de Cobalto , Intestinos/patologia , Larva , Fígado/patologia , Pulmão/patologia , Camundongos , Schistosoma/crescimento & desenvolvimento , Schistosoma/efeitos da radiaçãoRESUMO
The cutaneous hypersensitivity reaction in sheep infected with Dictyocaulus filaria was investigated. The saline extract of the worms increased the cutaneous capillary permeability in both the infected and uninfected control animals. Similar increase in the permeability was also observed in uninfected healthy rabbits. The results suggest that the vascular permeability increasing action of the worm extract is, partly, due to histamine release.